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Last update: 24/01/05 



The Bioinformatics Unit
The Center Of knowledge for Bioinformatics Infrastructure
present an INN workshop on

Finding the Needle in the Haystack -
Searching for Promoters in Genomic Sequence

Sunday 23.1.2005
at the Life Sciences Institute - Giv'at-Ram


Dr. Shifra Ben-Dor
INN- Israeli National Node of EMBNet
Bioinformatics and Biological Computing Unit
Biological Services
Weizmann Institute of Science
e-mail: shifra.ben-dor@weizmann.ac.il


Finding control regions of genes is one of the big "black boxes" of modern molecular biology. As more and more genomic sequence from various organisms becomes available, genes are becoming easier to find, but the control regions are still problematic. Many algorithms exist for predicting promoter regions, but all of them have high false positive/false negative rates. This workshop will cover the status of the major eukaryotic genomes sequenced to date, background on what promoter searching entails, and the various algorithms available for promoter searching


09:00-10:00 How genomes were sequenced and the states of common Eukaryotic Genomes
10:00-11:00 From mRNA to Genomic Sequence - Defining the Genomic Region
11:00-11:15 Coffee Break
11:15-12:00 How Do We Define a Eukaryotic Promoter?
12:00-13:00 Tools for Promoter Searching
13:00-13:45 Lunch Break
13:45-15:15 Hands-on


Lectures will take place at "Moadon Hasegel" at the life sciences institute.
Hands-on session will take place at the computer classroom on the third floor of the life sciences institute.

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